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Thursday, August 27, 2020
Marketing Psychology Essay Example | Topics and Well Written Essays - 1500 words
Advertising Psychology - Essay Example Purchaser Behavior Consumer conduct is a significant component of customer culture. When all is said in done, it is generally considered as the investigation of buying process for example how an individual purchases items. Be that as it may, this buy procedure study is only a piece of definition; it incorporates different components, which the accompanying definition clarifies: ââ¬Å"Consumer conduct mirrors the totality of consumerââ¬â¢s choice as for the obtaining, utilization, and mien of products, administrations, exercises, encounters, people groups, Ideas by (human) dynamic units (over time)â⬠(Wayne and Deborah, 2008, pg. 3). Purchaser conduct incorporates something beyond the way an individual purchases unmistakable items; it further incorporates a customer utilization of administrations, encounters, exercises and thoughts. Models would incorporate dynamic like going to an occasion, gift to a specific cause, arranging a get-away and so on (Wayne and Deborah, 2008, pg . 3). A customer way of purchasing is critical to advertisers. In any case, alongside it, advertisers are likewise exceptionally keen on buyer conduct identified with utilizing and discarding a contribution (Wayne and Deborah, 2008, pg. 4). As Mowen in 1995 characterized, ââ¬Å"Consumer conduct as the investigation of purchasing units and the trade procedure engaged with securing, expending and discarding nourishments, administrations, experience and ideasâ⬠(Apruebo, 2005, pg. 2). ... 5). Shopper Psychology Davis and Palladino (1995) characterized customer brain science, ââ¬Å"as the investigation that manages exercises straightforwardly engaged with choosing, acquiring, and utilizing items, administrations, and thoughts to fulfill needs, and wants, including dynamic procedure that go before and follow these actions.â⬠Simply, it is an applied part of brain science on buyer conduct (Apruebo, 2005, pg. 2). Customer brain research is a part of buyer conduct (Armstrong, Armstrong, and Kotler, 2007, pp. 250-325). Likewise, customer brain science is one of the significant viewpoints and components that impact shopper conduct, and it is the fundamental component of purchaser conduct since this is the thing that triggers a buyer towards utilization of good. It is the most starting or essential component on the grounds that while assessing the acquisition of an item, mental procedures are the initial step client takes part in. The client should be propelled, capable , and have the chance to be uncovered, to comprehend and use data (Bennet, 2009, pp. 30-36). A client need to consider the accessible data, build up a demeanor towards it and structure recollections. These are largely the mental parts of buyer conduct, investigation of which portrays purchaser brain research (Wayne and Deborah, 2008, p 11-12). Purchaser brain research for the most part manages why and how individuals purchase certain items and why not others. It is worried about how thinks, feeling, discernments, and considerations of a client effect on the selection of merchandise and ventures he buy. It includes of components like considerations, feeling, feelings connected to the item, ecological variable like family, companions, society, culture, individual elements and so on (Kendra, n.d). Contrast between Consumer Behavior
Saturday, August 22, 2020
A Memorable Term Essay
In Mr. Rodriguezââ¬â¢s Spanish 1-2 class, we have adapted such a significant number of new things and have had the astounding chance to acquire familiarity with another dialect. A portion of the objectives we had in the start of the term were to become familiar with the suitable degree of Spanish, for instance more information on action words, and how to state fundamental discussions and welcome. We were relied upon to have picked up all that we were instructed, and the essential piece of the Spanish language. Mr. Macfarland was our Spanish instructor, and his strategies were that we got our work done in schoolwork bundles, and we would sing our jargon, which profited us and helped us remember it in a simpler manner. At the point when we stepped through exam, tests and responded to questions so anyone might hear, he could pass judgment in the event that we were learning or not by the appropriate responses we would give, or the evaluations we would get. The family venture we did in Mr. Macfarlandââ¬â¢s class was unquestionably the most essential and charming task we did. All through my first year, I didnââ¬â¢t do whatever other venture that resembled the family venture we did in his group, and that is the thing that made it so pleasant. It was amusing to experience old pictures, and have the option to kind of acquaint youââ¬â¢re family with your group. I did well in my Spanish class, accepting high evaluations on most assignments. A portion of the challenges I encountered were doing schoolwork, since that was the main class I had schoolwork in regular and furthermore book work, since it was difficult to see here and there. I learned numerous new intriguing things; I figured out how to have a discussion in Spanish, additionally action words in Spanish. All through this term I have improved enormously. I have increased much more information, in light of the fact that in the start of the term the main thing I could state was hi. With respect to my accomplishments, I am pleased to the point that I got An in my group, since that was exceptionally past my desires. I would review my exertion about a B-, on the grounds that there were a great deal of times I would relax and not do schoolwork and my exhibition about a B since I now and again talked during that class however focused and quit fooling around when it was fundamental. Learning Spanish can profit me in my future since I will have the option to marginally grasp others when they are communicating in Spanish, which is significant in light of the fact that numerous individuals communicate in Spanish in San Diego. Likewise, I will keep learning Spanish for my sophomore year. I didn't have issues out of school that influence my homeroom experience. One year from now I might want to improve my exertion, and in the event that I keep taking Spanish in school it could help my transcript from having taken in a subsequent language. To arrive at my objectives sooner rather than later, I will keep taking dialects since I feel it is something I have to succeed and something I appreciate doing. During this Spanish class, I have had such a significant number of astonishing encounters it is too much. I will always remember how entertaining and odd Mr. Macintosh was. I will likewise always remember how he caused us to sing our jargon since I have always been unable to have a ton of fun while learning the importance of words. Generally, I have gained numerous experiences in this Spanish 1-2 class that I will always remember.
Friday, August 21, 2020
A Dolls House assignment Essay Example For Students
A Dolls House task Essay How does Henrik Ibsen use generalization in A Dolls House to challenge our pre-origination of sexual orientation jobs inside marriage? Ought to identify with bot present day and the time in which the play was set in.à In todays world, the cliché jobs that guys and females play in their relationships are altogether different from the time the play A Dolls House was set in. The play mirrored the English society in the mid nineteenth century. Ibsen depicted Torvald as the cliché spouse in those occasions. He was the pioneer and the provider of the family. He was ruling, disparaging and constantly treated Nora with mockery. Likewise, Nora was depicted as a cliché spouse. Her character was comprised of naivete. She was agreeable and subject to her significant other. Their relationship was loving however showed imbalance between the sexual orientation and this could be anticipated from in those occasions. In the main demonstration of the play, Ibsen indicated the composition which is the presentation of the play and its characters where not a lot occurs. He portrayed a typical group of those occasions and indicated that the lady of the house didn't invigorate a lot of feeling or freedom or. He demonstrated that Torvald was responsible for the cash he earned and Nora revealed to him how she went through the cash he had given her. Torvald treated her like an unpracticed youngster and revealed to her that she was a high-roller. In addition, she was even limited by him to eat macaroons and this demonstrated she couldn't do as indicated by her own wills yet needed to comply with her significant other. In any case, the peak of the play demonstrated that Nora disregarded the standards of the social standards of the time by obtaining cash from another man and keeping the reality escaped her significant other, despite the fact that it was to spare her better half from kicking the bucket. This shows Nora isn't as innocent as she was demonstrated to be nevertheless lets her better half feel that he has the force. She understood that what she had done wasn't right and her significant other would not favor of it. This was on the grounds that Torvald didn't care for in getting cash since it prompts obligation. However, Krogstad entangled the circumstance significantly more by demonstrating as a risk to this mystery as he was the loaner of the cash who concluded that if Torvald didn't keep his activity, he would be uncovered Noras mystery. This starts the test of the generalization of sexual orientation jobs inside marriage appeared by Ibsen. He demonstrated that such a circumstance, where a spouse resisted her better half, was not typical in those occasions. By the third demonstration, when Krogstad put a letter uncovering Nora of her mystery about the credit from Torvald, Nora was appeared in a more quiet way. Albeit caught, she trusted superb thing would happen when Torvald comes to know reality. She expected Torvald to acknowledge Krogstads conditions and assume the fault onto himself and excuse Nora and in this way yielding his respect for his cherished one. As opposed to her expectations and desires Torvald was not fearless enough for the penance. The superb thing didn't occur and Nora was broken. She was unable to acknowledge the way that her better half couldn't forfeit for her and left his life and this was totally against the cliché relationship inside a marriage life in the hour of the play. The test Ibsen set here demonstrated the uncommon jobs played by Nora and Torvald as a couple. Nora was shown as being increasingly free, developed, solid and certain. Then again, Torvald gives an indication of shortcoming, misery and powerlessness. Ibsen contradicted the cliché way significantly more by demonstrating that Nora leaves Torvald. This is an irregular demonstration to be taken up by ladies in those days as in the social orders, ladies were still viewed as the feeble or second rate sexual orientation of the two and don't by and large take up such goes about as they are accepted to be frail, guileless and subordinate. The other abnormality is Torvald who, in spite of the fact that, should have a place with the predominant sex loses at long last and is completely frail to the point that he needed to argue Nora to remain with him. .u6a58258233fe8ce12e5b5c1143a09b4c , .u6a58258233fe8ce12e5b5c1143a09b4c .postImageUrl , .u6a58258233fe8ce12e5b5c1143a09b4c .focused content zone { min-tallness: 80px; position: relative; } .u6a58258233fe8ce12e5b5c1143a09b4c , .u6a58258233fe8ce12e5b5c1143a09b4c:hover , .u6a58258233fe8ce12e5b5c1143a09b4c:visited , .u6a58258233fe8ce12e5b5c1143a09b4c:active { border:0!important; } .u6a58258233fe8ce12e5b5c1143a09b4c .clearfix:after { content: ; show: table; clear: both; } .u6a58258233fe8ce12e5b5c1143a09b4c { show: square; progress: foundation shading 250ms; webkit-change: foundation shading 250ms; width: 100%; darkness: 1; change: obscurity 250ms; webkit-progress: haziness 250ms; foundation shading: #95A5A6; } .u6a58258233fe8ce12e5b5c1143a09b4c:active , .u6a58258233fe8ce12e5b5c1143a09b4c:hover { mistiness: 1; change: murkiness 250ms; webkit-progress: obscurity 250ms; foundation shading: #2C3E50; } .u6a58258233fe8ce12e5b5c1143a09b4c .focused content region { width: 100%; position: relative ; } .u6a58258233fe8ce12e5b5c1143a09b4c .ctaText { outskirt base: 0 strong #fff; shading: #2980B9; text dimension: 16px; textual style weight: striking; edge: 0; cushioning: 0; content embellishment: underline; } .u6a58258233fe8ce12e5b5c1143a09b4c .postTitle { shading: #FFFFFF; text dimension: 16px; text style weight: 600; edge: 0; cushioning: 0; width: 100%; } .u6a58258233fe8ce12e5b5c1143a09b4c .ctaButton { foundation shading: #7F8C8D!important; shading: #2980B9; fringe: none; outskirt sweep: 3px; box-shadow: none; text dimension: 14px; text style weight: intense; line-stature: 26px; moz-fringe span: 3px; content adjust: focus; content enrichment: none; content shadow: none; width: 80px; min-stature: 80px; foundation: url(https://artscolumbia.org/wp-content/modules/intelly-related-posts/resources/pictures/straightforward arrow.png)no-rehash; position: supreme; right: 0; top: 0; } .u6a58258233fe8ce12e5b5c1143a09b4c:hover .ctaButton { foundation shading: #34495E!important; } .u6a58258 233fe8ce12e5b5c1143a09b4c .focused content { show: table; tallness: 80px; cushioning left: 18px; top: 0; } .u6a58258233fe8ce12e5b5c1143a09b4c-content { show: table-cell; edge: 0; cushioning: 0; cushioning right: 108px; position: relative; vertical-adjust: center; width: 100%; } .u6a58258233fe8ce12e5b5c1143a09b4c:after { content: ; show: square; clear: both; } READ: Research Investigation on Domestic Tragedy EssayHowever, in todays world, the sexual orientation jobs played inside the marriage are completely differentiating to those referenced previously. A cliché spouse doesn't need to play the reliant and devoted job and the husband doesn't really need to assume the job of a ruling individual of the family. Both the sexes have equivalent influence in the childhood of the family. Them two can work, gain and be the proprietor of their own lives without complying with each other. Moreover, separate has become an increasingly regular issue in todays world and this was not the situation in the time A Dolls House was set.
Evolution of building materials Essay Example for Free
Advancement of building materials Essay In part 12 we investigate the aesthetic advancement in Architecture. While conceptualizing a structure planners fuse three things: capacity, structure, and structure. Capacity is the manner by which the structure will be utilized, structure is the manner by which the structure looks, and structures is the means by which the structure stays standing. Engineers need to configuration structures that hold up under any blend of three physical powers; pressure, strain, and twisting. To days modelers have a plenty of materials at their isposal, they profit by the development of materials and have the chance to utilize them how they wish, yet it has not generally been like this. Crude structures were manufactured utilizing dry brick work, which is a straightforward procedure of stacking stones in a reliable example without utilizing any mortar. Structures, for example, the Great Pyramids of Egypt, and the Great Zimbabwe(190) in East Africa are ideal instances of this sort of brick work. In both of these structures the stones are dressed importance they are cut or molded before use. Post and pillar and curve structure frameworks were utilized predominately before the wentieth century, in places like Greece, Rome, and Egypt. The structure on post-and-bar structures needs to due with the materials utilized. Stone shafts must be shorter and thicker on the grounds that stone is fragile and not adaptable. Wood anyway is progressively adaptable so they can be thiner and longer thus they can be use to make an increasingly open inside space. Curve structure utilizes stone in a semi-hover on two segments or wharfs, greater renditions of sections, making a Round Arch. There is a stone put place that hold the curve together known as a cornerstone. At the point when a round curve is stretch out in an epth measurement, the impact is known as a Barrel Vault. At the point when two Barrel Vaults cross the purpose of convergence makes a Groin Vault. These kinds of structures were utilized by early human advancements of western Asia and the Mediterranean territory for underground depletes and tombs. Romans were the first to utilize the method over-the-ground and there had the option to utilize it to assemble things like the Roman Coliseum and the Pont du Gard(192), the reservoir conduit, which was both a scaffolds for movement just as an extension for water. At the point when a curve is pivoted 180 degrees it frames a vault, that is sed in to make immense inside space. Gothic style engineering presented another kind of curve, a sharp curve which took into account more extensive bases and a progressively pointed bend, however is utilizes no cornerstone. The nonappearance of the cornerstone makes a feeble structure that couldn't hold up under the pressure power. The make the flying brace, which is a help set at a 90 degree edge to the curve and holds the structure set up. The following significant advance in the development of Architecture was bracket and inflatable casing design. Brackets are triangular structure use to traverse air support, for example, a russ of house rooftop, or one utilized as a side of a scaffold. Inflatable encircling alludes to the utilization the supplanting of thick timbers with slight studs held together by just nails, from the start however of as unstable and feeble, yet is utilized today in lodging advancement. The development ot metals in the design world nave been enormous. T improvement of cast iron took into account structures to be set up rapidly, in light of the fact that it is stinger that wood or stone and can traverse more noteworthy separations, The Crystal Place was worked in just a half year and secured 19 sections of land of land, it was a wonder of the structure world. Next Came Steel and strengthened solid structures. The quality of steel outlines and the ongoing development of the lift took into consideration the first conceptualized and assembled high rises. This brought about the International Style meaning the utilization of present day material like glass, steel, and cement to make these sorts of structures. Domino Construction System, were six backings made of steel are set in solid pieces, lightens the requirement for help dividers, making the way for working for spaces for how they should be utilized, and the capacity to make dividers totally out of girl known as blind dividers. Carbon fiber is the most recent material to surface, not yet utilized for building, it is amazingly light, and solid. Engineers are currently conceptualizing how they may have the option to utilize this material later on. Carbon fiber can possibly upset the structure world. Many structure now days are attempting to arrive at an amicability with nature in both plan and vitality effectiveness. Structures like Guggenheim Museum Bilbao(200) are placing in to rehearse the regularly changing face of nature in the plan of the structures. Green uildings are jumping up wherever either new development or revamping existing structures to make them vitality productive and progressive simultaneously. They advancement of building materials and configuration take into account engineers of today the chance to actualize excellence in their structures. The capacity to fuse any material from stone steel and glass cement and wood into a structure has brought about a portion of the universes generally wonderful and exquisite structures going back to totally stone structure, to todays greetings rise structures, engineering is an excellent thing.
Friday, July 3, 2020
The Relationship Between Beta-Amyloid and Tau and Their Relation to Alzheimers Disease - Free Essay Example
The Relationship Between Beta-Amyloid and Tau and Their Reease affects over 40 million people in the world. It is a costly disease that robs the afflicted person of their mental capacity over a period of five to twenty years. In the United States alone, there are five and a half million people that have the disease (Alzheimers Association). Alzheimers Disease is also the only disease in the top ten leading causes of death in people over the age of 65 that cannot be cured, prevented, or slowed. What are researchers doing to try to prevent this disease? Researchers are currently taking steps by trying to figure out how beta-amyloid and tau relate to each other and how these two proteins play a role in Alzheimers Disease. Millions upon millions of dollars of research and hours have been spent in researching how to prevent this disease. Alzheimers Disease is currently the only disease in the top leading causes of death of people above the age of 65 that cannot currently be prevented, slowed, or cured. This presents a great challenge to researchers that want to help people afflicted with Alzheimers Disease and other types of mental degenerative diseases. To do that researchers must find out what causes Alzheimers Disease and what it is characterized by. Alzheimers Disease is currently a Subtype of Dementia. To understand it better, researchers must be able to understand what dementia is and the different stages that are included throughout the progression of the disease. Dementia is characterized by the continued loss of memory and mental function until the afflicted can no longer perform household tasks such as bathing and going to the bathroom. According to the Mayo Clinic, there are five different stages of Alzheimers Disease and these include: Preclinical Alzheimers Disease, MCI (Mild Cognitive Impairment), Mild Dementia, Moderate Dementia, and Severe Dementia (Mayo Clinic). Preclinical Alzheimers Disease is the first stage in this disease. Preclinical Alzheimers Disease takes place years before any noticeable symptoms can be observed. There are many changes going on in the brain during this period. There are noticeable signs in the brains structure but a person does not show a cognitive decline. The people around someone with Preclinical Alzheimers Disease will not be able to notice anything different about the person that has it. Neither will the person afflicted. This stage is often the longest stage of the disease because the onset is very gradual and can take decades to progress to the next stage of the disease. This stage also goes undetected because you would need to have tests that show the brain with a baseline and follow up tests for comparison. The second stage of Alzheimers Disease is Mild Cognitive impairment or MCI. MCI has little effect on work and social life. People with MCI may tend to have memory lapses or difficult remembering the steps of how to do something. This stage usually lasts about two years before it advances into the next stage of Alzheimers Disease. It is also important to note that people with MCI do not always have Alzheimers Disease but that people with Alzheimers disease will go through the MCI stage of the disease. The next stage in Alzheimers Disease is mild dementia. People with Alzheimers are mostly diagnosed with the disease in this stage because of the significant increase in trouble with cognitive tasks. Individuals in this stage will often ask the same question multiple times because they cannot remember the answer to it as well as having difficulty solving complex problems. They may also have difficulty expressing thoughts and expressing themselves, and possibly go though personality changes. These personality changes are different based on the person, but one may be more irritable or become more withdrawn in social situations. Moderate dementia is the next stage in Alzheimers Disease. Individuals in this stage should no longer be left to care for themselves because of their cognitive decline. They show increasingly poor judgement and have trouble making good decisions. They also experience an even greater loss of memory and more major personality changes. Individuals may mistake family members and friends as the same person and strangers as family members. It is not uncommon for individuals in this stage of Alzheimers Disease to think that people are stealing from them or see and hear things that are not there. People may forget to do daily activities such as eating and drinking or may not be able to find the bathroom and should no longer be left to live on their own. Severe dementia is the last stage in Alzheimers Disease. It can also be called advanced dementia or late stage dementia. During this stage ones ability to do daily tasks is no longer there and they need a full time caregiver. Commonly one will also lose the ability to speak coherently and can no longer communicate what they want or need to their caregiver. Many people do not make it to this stage of the disease but those that do are expected to live one to three years. Alzheimers Disease can last for up to twenty years but most that are diagnosed with the disease only live about six to twelve years after the diagnosis. The factors in how long someone that has will live are various. There are genetic factors that can speed up or slow down the process as well as simple things such as diet and activity level. There are many different factors that go into developing Alzheimers Disease, but researchers agree that there are two proteins in the brain that are mostly to blame. According to the World Alzheimers report 2018, One is called beta-amyloid, usually just called amyloid the other is called tau (Patterson, 8). These two proteins reach levels both reach abnormally high levels are start to prevent cognitive function. Scientists currently do not know why these proteins rise to these abnormally high levels or what relationship they have to each other. To try to understand more about how to prevent and cure the disease scientists must look at what each of these proteins do to the brain. Amyloid is a fragment of the amyloid precursor protein. According to PDB-101: Acetylcholine Receptor, It [the amyloid precursor protein] is a large membrane protein that normally plays an essential role in neural growth and repair. However, later in life, a corrupted form can destroy nerve cells, leading to the loss of thought and memory in Alzheimers disease (PDB-101: Acetylcholine Receptor). This protein is a very important part of neural growth and for that reason, researchers say that they cannot simply just shut off the production of this protein. So what happens next? The problem isnt with the amyloid precursor protein (APP) but with what it leaves behind after it has been used. What is left behind is commonly called beta-amyloid. In younger people, this toxic fragment is recycled by the body and cannot harm the brain cells. In individuals with Alzheimers Disease, the protein is not broken down fast enough which results in the toxic fragments of APP bonding together and forming a plaque. This buildup causes two different things to happen because of the properties it possesses. The properties that the built up amyloid has is that it is toxic to the brain cells, and the plaques also restrict any possible growth in the brain. Amyloid also causes mutations in different cells and proteins in the brain. This causes a mutation in tau which is the other protein in the brain that is a major factor in why the tau protein starts to become toxic to the brain. Tau is a protein in the brain that helps build the structure of the brain itself. According to Eva-Maria Mandelkow and Eckhard Mandelkow, Tau was one of the first microtubule-associated proteins (MAPs) to be characterized(Mandelkow, E.-M., and E. Mandelkow). Microtubules are structures that help transport materials used in cells be transported as well as helping provide the so called scaffolding of the brain. Tau helps bind these microtubules to the cells and to each other(Hyman et al.). Unlike other proteins, tau does not fold itself and is a very long molecule in the body. According to Eva-Maria Mandelkow and Eckhard Mandelkow, Tau is normally a cytosolic protein, but its occurrence outside cells has become important for studying and diagnosing the Alzheimers Disease disease process(Mandelkow, E.-M., and E. Mandelkow). Since tau can be found outside of cells, it builds up in the the cerebrospinal fluid (CSF) at an early stage of Alzheimers Disease and therefore serves as a biomarke r (Mandelkow, E.-M., and E. Mandelkow). Tau is also a very important protein to the brain and the rest of the body which is why researchers must try to find another way to prevent it from mutating and becoming toxic to the brain instead of just trying to limit the amount the the body can produce like they can with other proteins that play a less important role. When this protein mutates it starts to bond to itself instead of other cells that it normally bonds to. Because this protein can be outside of the cells in the brain, it can form clumps called neurofibrillary tangles. According to the Bright Focus Foundation, Neurofibrillary tangles are insoluble twisted fibers found inside the brains cells. These tangles consist primarily of a protein called tau, which forms part of a structure called a microtubule (Bright Focus Foundation). This causes the protein to become toxic to the brain itself even though it is an essential protein in the body. It starts to cause the brain calls to shrink and die. It also starts to block neu ral pathways as well which is what causes the majority of memory loss in Alzheimer patients. So how do these two proteins relate to each other? When amyloid is not broken down it starts to build plaques that restrict brain growth and causes mutations. One of these mutations happens to the tau protein in the brain which plays an important role in creating the brain structure. When this protein mutates, it rises to abnormal levels and starts to bond to itself. This then allows for tau protein clumps called neurofibrillary tangles to to become toxic to the brain tissue and also block neural pathways. There is also another factor that these two proteins have on the brain. When these two molecules reach abnormal levels, they start to interact with each other. Amyloid starts to encase the tau protein clumps. When this happens they create another toxic element to the brain. When these two molecules interact they also amplify the toxic effects that each one has on the brain resulting with a compounding effect. Interestingly enough, according to Small and Duff, mutations in both genes encoding APP and tau were found to cause dementing illness(Small, Scott A., and Karen Duff). Since amyloid plaques also cause more mutations in the genes of cells, it can cause this same mutation that causes tau to form neurofibrillary tangles inside of neurons. Scientists have come up with a way to possibly cure Alzheimers Disease. When the amyloid protein starts reaching abnormal levels, there is a short period of time during the preclinical phase of Alzheimers Disease that a amyloid reducing pharmacological agent can be introduced into the brain. According to small and duff, a pharmacological agent that reduces brain A levels should act as an effective drug against the disease (Small and Duff). This is a very promis In total, Alzheimers Disease is a very devastating disease that is very complicated. Tau and beta-amyloid play big roles in causing each other to rise to abnormal level and both play a big role in causing Alzheimers Disease. Only in recent years, researchers have just found out what causes the brain to decline in cognitive function at such a significant rate. There are five stages going from no symptoms at all to completely robbing someone of their ability to live on their own and make choices for themselves. Two major proteins that are responsible for causing AD are beta-amyloid and tau. Each of these toxic factors to the brain come from things that play a major role in brain structure and development. There are some things that scientists can do to attempt to slow down the progression of the diseaseand maybe even cure it but is ineffeective due to the fact that by the time one knows they have AD, the disease has already started a wildfire that is breaking down their brain and scien tists do not know how to stop this from happening in the brain. Works Cited Amyloid Plaques and Neurofibrillary Tangles. BrightFocus Foundation, 28 Nov. 2018, www.brightfocus.org/alzheimers-disease/infographic/amyloid-plaques-and-neurofibrillary-tangles. Mandelkow, E.-M., and E. Mandelkow. Biochemistry and Cell Biology of Tau Protein in Neurofibrillary Degeneration. Cold Spring Harbor Perspectives in Medicine, vol. 2, no. 7, 2012, doi:10.1101/cshperspect.a006247. PDB101: Molecule of the Month: Amyloid-Beta Precursor Protein. PDB-101: Acetylcholine Receptor, pdb101.rcsb.org/motm/79. Rajmohan, Ravi, and P. Hemachandra Reddy. Amyloid-Beta and Phosphorylated Tau Accumulations Cause Abnormalities at Synapses of Alzheimers Disease Neurons. Journal of Alzheimers Disease, vol. 57, no. 4, 2017, pp. 975ââ¬Å"999., doi:10.3233/jad-160612. Small, Scott A., and Karen Duff. Linking A and Tau in Late-Onset Alzheimers Disease: A Dual Pathway Hypothesis. Neuron, vol. 60, no. 4, 2008, pp. 534ââ¬Å"542., doi:10.1016/j.neuron.2008.11.007. Spires-Jones, Tara L., and Bradley T. Hyman. The Intersection of Amyloid Beta and Tau at Synapses in Alzheimers Disease. Neuron, vol. 82, no. 4, 2014, pp. 756ââ¬Å"771., doi:10.1016/j.neuron.2014.05.004. Stages of Alzheimers. Alzheimers Association, Alzheimers Association, www.alz.org/alzheimers-dementia/stages. Wortmann, Marc. World Alzheimer Report 2014: Dementia and Risk Reduction. Alzheimers Dementia, vol. 11, no. 7, 2015, doi:10.1016/j.jalz.2015.06.1858.
Tuesday, May 26, 2020
Overview of iron and steel industry - Free Essay Example
Sample details Pages: 3 Words: 800 Downloads: 6 Date added: 2017/06/26 Category Statistics Essay Did you like this example? OVERVIEW OF IRON AND STEEL INDUSTRY Introduction Steel is crucial to the development of any modern economy and is considered to be the backbone of human civilisation. The level of per capita consumption of steel is treated as an important index of the level of socioeconomic development and living standards of the people in any country. It is a product of a large and technologically complex industry having strong forward and backward linkages in terms of material flows and income generation. Donââ¬â¢t waste time! Our writers will create an original "Overview of iron and steel industry" essay for you Create order All major industrial economies are characterised by the existence of a strong steel industry and the growth of many of these economies has been largely shaped by the strength of their steel industries in their initial stages of development. Steel industry was in the vanguard in the liberalisation of the industrial sector and has made rapid strides since then. The new greenfield plants represent the latest in technology. Output has increased, the industry has moved up in the value chain and exports have risen consequent to a greater integration with the global economy. The new plants have also brought about a greater regional dispersion easing the domestic supply position notably in the western region. At the same time, the domestic steel industry faces new challenges. Some of these relate to the trade barriers in developed markets and certain structural problems of the domestic industry notably due to the high cost of commissioning of new projects. The domestic demand too has not imp roved to significant levels. The litmus test of the steel industry will be to surmount these difficulties and remain globally competitive. Historical Perspective The finished steel production in India has grown from a mere 1.1 million tonnes in 1951 to 31.63 million tonnes in 2001-2002. During the first two decades of planned economic development, i.e. 1950-60 and 1960-70, the average annual growth rate of steel production exceeded 8%. However, this growth rate could not be maintained in the following decades. During 1970- 80, the growth rate in steel production came down to 5.7% per annum and picked up marginally to 6.4% per annum during 1980-90, which further increased to 6.65% per annum during 1990-2000. Though India started steel production in 1911, steel exports from India began only in 1964. Exports in the first five years were mainly due to recession in the domestic iron and steel market. Once domestic demand revived, exports declined. India once again started exporting steel only in 1975 touching a figure of 1 million tonnes of pig iron and 1.4 million tonnes of steel in 1976-77. Thereafter, exports again declined to pick up only in 1 991-92, when the main producers exported 3.87 lakh tonnes, which rose to 2.79 million tonnes in 1995-96 and 3.3 million tonnes in 2001-02. The growth in the steel sector in the early decades after Independence was mainly in the public sector units set up during this period. The situation has changed dramatically in the decade 1990-2000 with most of the growth originating in the private sector. The share of public sector and private sector in the production of steel during 1990-91 was 46% and 54% respectively, while during 2001-02 the same was 32% and 68% respectively. This change was brought about by deregulation and decontrol of the Indian iron steel sector in 1991. A number of policy measures have been taken since 1991 for the growth and development of the Indian iron steel sector. Some of the important steps are (a) removal of iron steel industry from the list of industries reserved for the public sector and also exempting it from the provisions of compulsory licensing under t he Industries (Development Regulation) Act, 1951, (b) deregulation of price and distribution of iron steel, (c) inclusion of iron and steel industry in the list of high priority industries for automatic approval for foreign equity investments upto 51%. This limit has been since increased upto 100%, (d) lowering of import duty on capital goods and raw materials etc. Growth of the Indian Steel Sector after Liberlisation Finished Carbon Steel The Indian steel sector was the first core sector to be completely removed from the licensing regime as well as pricing and distribution controls. This was done primarily because of the inherent strengths and capabilities demonstrated by the Indian iron and steel industry. The growth rate in 1995-96 was a phenomenal 20%. During 1996-97, finished steel production shot up to a record 22.72 million tonnes with a growth rate of 6.2%, while in 1997-98, the finished steel production increased to 23.37 million tonnes, which was 2.8% more than the production of the preceding year. The growth rate decreased drastically in 1997-98 and 1998-99 being 2.8% and 1.9% respectively. The growth rate in 2001-2002 was 4.29% with the total production touching 31.63 million tonnes. The production of finished steel during April December, 2002 has been 23.83 million tonnes, which is 6.3% higher than the production during the corresponding period of 2001-02. Details of total production of finished carbon ste el and the share of main
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